Factory Wholesale Cosmetics Grade Deoxyarbutin 99%

Short Description:

Product Name: Deoxyarbutin
Specifications: ≥99%
Appearance: White powder
Certificate: GMP、Halal、kosher、ISO9001、ISO22000
Shelf Life: 2 Year

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Introduction

Deoxyarbutin is a new generation cosmetic skin brightening and whitening active agent. It is mainly used in advanced whitening cosmetics. It can effectively inhibit tyrosinase activity, regulate melanin production, overcome pigmentation, and lighten black spots on the skin. It has rapid and long-lasting effects. skin whitening effect. Deoxyarbutin also has strong antioxidant effects.

The inhibitory effect of deoxyarbutin on tyrosinase is significantly better than other whitening active agents. The whitening effect is 350 times that of arbutin, 150 times that of kojic acid, and 10 times that of hydroquinone. Compared with the former, it is safer High, more stable, not only non-toxic and non-irritating to the skin, but also easily absorbed by the skin. It can show whitening and brightening effects with a small amount of use. It is considered a very safe cosmetic whitening active agent.

Application

Deoxyarbutin, as a new generation of cosmetics skin brightening and whitening active agent, is mainly used in advanced whitening cosmetics.

D-Arbutin is one of the derivatives of arbutin, called D-arbutin, which can effectively inhibit the action of tyrosinase in skin tissue. According to research, its potency is even 10 times that of hydroquinone. 350 times that of ordinary arbutin. In animal skin tests, this D-Arbutin can quickly and effectively whiten the skin, and the effect can still be maintained for nearly 8 weeks after stopping use.

In human clinical studies, topical use of D-Arbutin for 12 weeks can achieve obvious skin lightening effects, and it has a good improvement effect on sun-exposed spots and dull skin tone. Clinical research on D-Arbutin further pointed out that many tyrosinase inhibitors have been used in the past to reduce skin lesions caused by melanin accumulation. D-Arbutin produced using QSAR (quantitative structure-activity relationships) technology is a very effective The tyrosinase inhibitory ingredient has a significant blocking effect on the formation of melanin in the skin.

When you stop using D-Arbutin, the tyrosinase enzyme function and melanin content in the skin will slowly recover. This means that D-Arbutin will not cause the poisoning effect of melanocytes and can allow melanocytes to still maintain normal physiological mechanisms. . In an 8-week clinical study, topical application of D-Arbutin resulted in gradual but significant skin lightening effects. Another clinical study further pointed out that using an appropriate concentration of D-Arbutin solution can achieve good clinical effects within 3 weeks. And according to experiments, the effectiveness of D-Arbutin against melanin can reach 10 times that of hydroquinone, 150 times that of kojic acid, and 350 times that of ordinary arbutin (β-arbutin). If compared with the popular α-arbutin If so, it would be 38.5 times higher.

Certificate of Analysis

Product Name:		Deoxyarbutin		Manufacture Date:		2023-09-30
Batch No.:		Ebos-230930		Test Date:		2023-09-30
Quantity:		25kg/Drum		Expiration Date:		2025-09-29

ITEMS		SPECIFICATION				RESULT
Assay(HPLC)		≥99.0%				99.7%
Appearance		White crystals or crystalline powder, IR spectrum conforms				Conforms
Loss on Drying		≤0.5%				0.07%
Residue on Ignition		≤0.5%				0.05%
Transparency in water		Transparent colorless no suspended				Conforms
PH（1% water solution）		5.0-7.0				6.16
Melting Point		199~201±0.5℃				199.5~200.7
Hydroquinone		Negative				Negative
Lead(mg/kg)		≤10				<10
Arsenic(mg/kg)		≤2				<2
Mercury(mg/kg)		≤1				<1
Methanol(mg/kg)		≤2000				<1000
Plumbum		<2ppm				Conforms
Aerobic bacterial Count		≤1000cfu/g				Conforms
Total Yeast & Mold		≤100cfu/g				Conforms
Fecal Coliforms		Negative				Negative
Pseudomonas Aeruginosa		Negative				Negative
Staphylococcus		Negative				Negative
Conclusion		Conform to the specification of the requirement.
Storage		Store in a cool and dry place, keep away from direct strong and heat.
Shelf Life		Two years if sealed and store away from direct sun light.
Tester	01	Checker	06		Authorizer		05

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