Cosmetic Grade Arbutin CAS NO 497-76-7 Beta-arbutin for Skin Whitening

Short Description:

Product Name:Beta-arbutin

Specifications: ≥99%

Appearance: White powder


Shelf Life:2 Year

Product Detail

Product Tags


Arbutin, also known as arbutin, is an ingredient extracted from bearberry leaves of the Rhododendron plant. It can prevent the production of melanin by inhibiting the activity of tyrosinase in the body, thereby reducing skin pigmentation and removing stains. and freckles. It also has bactericidal and anti-inflammatory effects and is used in cosmetics.

Arbutin is found in many plants, including some common herbs and foods. It is a flavonoid glycoside, divided into two forms: α-arbutin and β-arbutin. Although the chemical structures of the two are similar, there are differences in their pharmacological and biological activities.


Arbutin is an ideal whitening agent for whitening cosmetics. It is also called hydroquinone glucoside. It has two optical isomers, namely α and ß types. The ß isomer is the most biologically active.  β-Arbutin is a white slightly yellowish powder at room temperature. It is easily soluble in water, methanol, ethanol, propylene glycol, and glycerol aqueous solutions. There is no precipitation after dissolution. It is insoluble in chloroform, ether, petroleum ether, etc. It is added to many whitening skin care products.

Arbutin, also known as arbutin, refers to an active substance extracted from the leaves or fruits of bearberry. It is a white needle-shaped crystal or powder that combines "green plant, safe and reliable" and "efficient decolorization". An all-in-one skin depigmentation component, it can quickly penetrate into the skin. Without affecting the concentration of cell proliferation, it can effectively inhibit the activity of tyrosinase in the skin, block the formation of melanin, and directly bind to tyrosinase by itself. , accelerates the decomposition and excretion of melanin, thereby reducing skin pigmentation, removing spots and freckles, and does not produce toxic, irritating, sensitizing and other side effects on melanocytes. It also has bactericidal and anti-inflammatory effects.


Certificate of Analysis

Product Name:

Beta Arbutin

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Assay ≥99% 99.99%   HPLC
Physical Characteristics
Appearance White crystalline powder Conforms
Hydroquinone Negative Negative
Melting Point 203-206(±1)℃ 203.9-205.6 ℃
Specific Optical Rotation [a]20D= + 174.0°- +186.0° +179.81°
Infrared peak value 1514cm-1; 1229 cm-1; 1215 cm-1; 1059 cm-1; 1034 cm-1 1514cm-1; 1229 cm-1; 1215 cm-1; 1059 cm-1; 1034 cm-1
Solubility Soluble in water, slightly soluble in ethanol Conforms
Clarity Solution should be clarify, none suspended matters Conforms
PH (1% water solution) 5.0-7.0 6.28
Loss on drying ≤0.5% 0.01%
Residue on Ignition ≤0.5% 0.01%
Heavy Metals
Heavy metals ≤10ppm Conforms
Lead ≤2ppm Conforms
Arsenic ≤2ppm Conforms
Mercury ≤1ppm Conforms
Microbiological Tests
Total Plate Count ≤100cfu/g Conforms
Total Yeast & Mold ≤50cfu/g Conforms
E.Coli Negative Negative
Salmonella Negative Negative


Conform to the specification of the requirement.


Store in a cool and dry place, keep away from direct strong and heat.

Shelf Life

Two years if sealed and store away from direct sun light.







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